SCHEMBL344669

SCHEMBL344669

CC(C)(C)OC(=O)N[C@@H](CC(=O)OCc1ccccc1)C(=O)O

nearest known ligand 0.63

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 5/20 0.63
KLK5 Q9Y337 2/20 0.62
KLK7 P49862 1/20 0.62
PPARG P37231 4/20 0.58
ACE P12821 1/20 0.56
SYK P43405 1/20 0.54
CTSS P25774 4/20 0.54
CTSK P43235 3/20 0.52
PPARD Q03181 2/20 0.52
CTSL P07711 1/20 0.52
CTSB P07858 1/20 0.52
CACNA1B Q00975 4/20 0.51
MMP9 P14780 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL344670 1.00 PPARA (0.63) PPARAKLK5KLK7PPARGACE
SCHEMBL84710 1.00 PPARA (0.63) PPARAKLK5KLK7PPARGACE
SCHEMBL10585294 0.92 KLK5 (0.65) PPARAKLK5KLK7PPARGACE
SCHEMBL12585497 0.92 KLK5 (0.65) PPARAKLK5KLK7PPARGACE
SCHEMBL9943562 0.92 KLK5 (0.65) PPARAKLK5KLK7PPARGACE
SCHEMBL4370045 0.92 KLK5 (0.65) PPARAKLK5KLK7PPARGACE
SCHEMBL9943561 0.92 KLK5 (0.65) PPARAKLK5KLK7PPARGACE
SCHEMBL5870038 0.91 KLK5 (0.64) PPARAKLK5KLK7PPARGACE
SCHEMBL14300984 0.91 KLK5 (0.64) PPARAKLK5KLK7PPARGACE
SCHEMBL14300985 0.91 KLK5 (0.64) PPARAKLK5KLK7PPARGACE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 567 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119775348-A Preparation method of polypeptide Angstrom Pi Dalong acetate 深圳市第二人民医院(深圳市转化医学研究院) 2025-04-08 CN claimed
CN-119431221-A Synthesis method of chiral intermediate of gemagliptin 安徽峆一药业股份有限公司 2025-02-14 CN claimed
CN-115787325-B Polyester low-temperature dyeing promoter and preparation method thereof 太仓宝霓实业有限公司 2024-08-09 CN claimed
CN-111825742-B Polypeptide solid phase synthesis of CTPA as special coupling agent for amino acid ionic liquid 陈铭 2024-01-30 CN claimed
CN-115787325-A Polyester low-temperature dyeing accelerant and preparation method thereof 太仓宝霓实业有限公司 2023-03-14 CN claimed
CN-115490684-A 3S-1,2,3, 4-tetrahydro-beta-carboline-3-methyl-amino acid, preparation thereof, antithrombotic activity and application thereof 首都医科大学 2022-12-20 CN claimed
CN-115477648-A Carboline derivative, preparation method thereof and application thereof in preparing antitumor drugs 首都医科大学 2022-12-16 CN claimed
CN-102796169-B Double saturated aliphatic chain alcohol Glu-Asp-Gly-Asp tetrapeptide esters and preparation method and application thereof UNIV CAPITAL MEDICAL SCIENCES 2014-01-29 CN claimed
CN-102796169-A Double saturated aliphatic chain alcohol Glu-Asp-Gly-Asp tetrapeptide esters and preparation method and application thereof UNIV CAPITAL MEDICAL 2012-11-28 CN claimed
US-6306203-B1 FOR USE IN INK JET PRINTING, INCLUDING PIEZOELECTRIC INK JET PRINTING AND ACOUSTIC INK JET PRINTING XEROX CORPORATION 2001-10-23 US claimed
US-12612429-B2 Derivatives of dolaproine-dolaisoleuine peptides AGENSYS, INC. (US) 2026-04-28 US disclosed
EP-4729561-A1 POLYETHYLENE GLYCOL DRUG, AND PREPARATION METHOD THEREFOR AND USE THEREOF Chongqing Upgra Biotechnology Co., Ltd. (CN) 2026-04-22 EP disclosed
US-20260091082-A1 CYCLIC PEPTIDE DERIVATIVE COMPOSITION FOR TREATING OR PREVENTING EYE DISEASE DKS CO. LTD. (JP) 2026-04-02 US disclosed
US-20260071353-A1 SUBSTRATES, PEPTIDE ARRAYS, AND METHODS VIBRANT HOLDINGS LLC (US) 2026-03-12 US disclosed
US-12564583-B2 Small molecules against cereblon to enhance effector T cell function Lee Moffitt Cancer Center and Research Institute, Inc. (US) 2026-03-03 US disclosed
US-4629736-A HIGH FIBRINOLYTIC ACTION; WATER SOLUBILITY; ANTICOAGULANTS YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) 1986-12-16 US disclosed
US-4600705-A Gonadoliberin derivatives containing a β-aspartyl group, a process for the preparation thereof and pharmaceutical preparations containing them Richter Gedeon Veyteszeti Gyar R.T. (HU) 1986-07-15 US disclosed
US-4529549-A Compound containing guanidine and amino groups ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) 1985-07-16 US disclosed
EP-0136879-A2 Fatty acid derivatives and processes of producing them YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) 1985-04-10 EP disclosed
EP-0105193-A2 Spergualin-related compounds, processes for the preparation thereof and their use as medicaments MICROBIAL CHEMISTRY RESEARCH FOUNDATION (JP) 1984-04-11 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260091082-A1 CYCLIC PEPTIDE DERIVATIVE COMPOSITION FOR TREATING OR PREVENTING EYE DISEASE ADCY3, GLP1R, PDE6C PPARA 1053/4885KLK5 2592/4885KLK7 2792/4885
US-20260071353-A1 SUBSTRATES, PEPTIDE ARRAYS, AND METHODS VIP, CALCB, SPPL2B PPARA 3535/4885KLK5 1413/4885KLK7 678/4885
US-12612429-B2 Derivatives of dolaproine-dolaisoleuine peptides DDOST, NGLY1, GRPR PPARA 4569/4885KLK5 3192/4885KLK7 2129/4885
US-12564583-B2 Small molecules against cereblon to enhance effector T cell function CRBN, CD4, ICOS PPARA 2297/4885KLK5 4629/4885KLK7 4294/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.