Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.65 |
| ▸ | KIT | P10721 | 2/20 | 0.65 |
| ▸ | CLK1 | P49759 | 1/20 | 0.64 |
| ▸ | BRAF | P15056 | 2/20 | 0.64 |
| ▸ | ATM | Q13315 | 2/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.63 |
| ▸ | HCK | P08631 | 2/20 | 0.61 |
| ▸ | NR2C2 | P49116 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 3/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.61 |
| ▸ | MAP3K7 | O43318 | 2/20 | 0.61 |
| ▸ | MAP4K2 | Q12851 | 2/20 | 0.61 |
| ▸ | FES | P07332 | 1/20 | 0.61 |
| ▸ | FER | P16591 | 1/20 | 0.61 |
| ▸ | GCK | P35557 | 1/20 | 0.61 |
| ▸ | MAP3K20 | Q9NYL2 | 2/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29562197 | 0.92 | KIT (0.77) | KITBRAF | |
| SCHEMBL14318406 | 0.92 | KIT (0.77) | KITBRAF | |
| Hydrochloric Acid SCHEMBL29833672 | 0.91 | KIT (0.75) | KITBRAF | |
| SCHEMBL30032225 | 0.90 | KIT (0.66) | KITBRAF | |
| SCHEMBL27997207 | 0.88 | KIT (0.61) | HTTKITCLK1BRAFMAPT | |
| SCHEMBL30309801 | 0.88 | KIT (0.69) | HTTKITCLK1BRAFATM | |
| SCHEMBL26680109 | 0.88 | KIT (0.69) | HTTKITCLK1BRAFATM | |
| SCHEMBL3389535 | 0.87 | HTT (0.71) | HTTKITCLK1BRAFATM | |
| SCHEMBL16236899 | 0.87 | KIT (0.86) | HTTKITCLK1BRAFATM | |
| SCHEMBL27088109 | 0.87 | RET (0.64) | HTTKITCLK1BRAFATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3473624-B1 | NOVEL IMIDAZOPYRIDINE DERIVATIVE, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME AS ACTIVE INGREDIENT FOR PREVENTING OR TREATING CANCER | DAEGU GYEONGBUK MEDICAL INNOVATION FOUND (KR) | 2022-05-11 | — | — | EP | disclosed |
| CN-103467385-B | Bicyclic heteroaryl compounds | ARIAD GENE THERAPEUTICS INC. (US) | 2016-03-09 | — | — | CN | disclosed |