SCHEMBL2805448

SCHEMBL2805448

CCOC(=O)c1c[nH]c2c(Cl)c(Cl)ccc2c1=O

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CLEC4M Q9H2X3 1/20 0.67
CSNK2A2 P19784 2/20 0.63
CSNK2B P67870 2/20 0.63
CSNK2A1 P68400 2/20 0.63
KDM4E B2RXH2 3/20 0.61
MAPT P10636 2/20 0.61
CYP1A2 P05177 1/20 0.59
CYP3A4 P08684 1/20 0.59
CYP2C19 P33261 1/20 0.59
KMT2A Q03164 3/20 0.57
MEN1 O00255 2/20 0.57
GABRA1 P14867 3/20 0.54
GABRB2 P47870 3/20 0.54
GABRB1 P18505 2/20 0.53
GABRA3 P34903 2/20 0.53
ALDH1A1 P00352 2/20 0.46
TP53 P04637 1/20 0.46
HPGD P15428 1/20 0.46
HSD17B10 Q99714 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16341803 0.85 CLEC4M (0.78) CLEC4MCSNK2A2CSNK2BCSNK2A1KDM4E
SCHEMBL18984770 0.81 CLEC4M (0.63) CLEC4MCSNK2A2CSNK2BCSNK2A1KDM4E
SCHEMBL28289147 0.80 CLEC4M (0.74) CLEC4MCSNK2A2CSNK2BCSNK2A1KDM4E
SCHEMBL7225478 0.80 CLEC4M (0.66) CLEC4MKDM4EMAPTCYP1A2CYP3A4
SCHEMBL28287784 0.80 CLEC4M (0.82) CLEC4MKDM4EMAPTCYP1A2CYP3A4
SCHEMBL11195663 0.80 CLEC4M (0.78) CLEC4MKDM4EMAPTCYP1A2CYP3A4
SCHEMBL30824246 0.79 CLEC4M (0.57) CLEC4MCSNK2A2CSNK2BCSNK2A1KDM4E
SCHEMBL20600361 0.79 CLEC4M (0.57) CLEC4MCSNK2A2CSNK2BCSNK2A1KDM4E
SCHEMBL15999534 0.79 CLEC4M (0.64) CLEC4MCSNK2A2CSNK2BCSNK2A1KDM4E
SCHEMBL11641095 0.79 CYP1A2 (0.63) CLEC4MCSNK2A2CSNK2BCSNK2A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100320428-A1 GASEOUS DIELECTRICS WITH LOW GLOBAL WARMING POTENTIALS HONEYWELL INTERNATIONAL INC. (US) 2010-12-23 US disclosed
US-7807074-B2 Gaseous dielectrics with low global warming potentials HONEYWELL INTERNATIONAL INC. (US) 2010-10-05 US disclosed
CN-101601103-A Gaseous Dielectrics with Low Global Warming Potential HONEYWELL INT INC (US) 2009-12-09 CN disclosed
US-20080135817-A1 Gaseous dielectrics with low global warming potentials HONEYWELL INTERNATIONAL INC. 2008-06-12 US disclosed