Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLEC4M | Q9H2X3 | 1/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.53 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.53 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.52 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25208357 | 0.87 | CLEC4M (0.63) | CLEC4MKDM4EMAPTCYP1A2CYP3A4 | |
| SCHEMBL29145962 | 0.86 | CLEC4M (0.62) | CLEC4MKDM4EMAPTCYP1A2CYP3A4 | |
| SCHEMBL30697790 | 0.86 | CLEC4M (0.62) | CLEC4MKDM4EMAPTCYP1A2CYP3A4 | |
| SCHEMBL29376920 | 0.85 | CYP1A2 (0.66) | CLEC4MKDM4EMAPTCYP1A2CYP3A4 | |
| SCHEMBL9635290 | 0.85 | CYP1A2 (0.66) | CLEC4MKDM4EMAPTCYP1A2CYP3A4 | |
| SCHEMBL2658932 | 0.85 | KDM4E (0.73) | CLEC4MKDM4EMAPTCYP1A2CYP3A4 | |
| SCHEMBL1126279 | 0.84 | CLEC4M (0.78) | CLEC4MKDM4EMAPTCYP1A2CYP3A4 | |
| SCHEMBL11235716 | 0.83 | CYP1A2 (0.63) | CLEC4MKDM4EMAPTCYP1A2CYP3A4 | |
| SCHEMBL1550705 | 0.81 | CLEC4M (0.58) | CLEC4MKDM4EMAPTCYP1A2CYP3A4 | |
| SCHEMBL10519082 | 0.81 | CYP1A2 (0.60) | CLEC4MKDM4EMAPTCYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6566362-B2 | Use as topical antibiotics | AVENTIS PHARMA S.A. (FR) | 2003-05-20 | — | — | US | disclosed |
| US-20020137741-A1 | Benzo[f]naphthyridine derivatives, their preparation and compositions containing them | AVENTIS PHARMA S.A. (FR) | 2002-09-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020137741-A1 | Benzo[f]naphthyridine derivatives, their preparation and compositions containing them | KCNQ2, KCNQ1, KCNQ4 | CLEC4M 4141/4885KDM4E 1398/4885MAPT 2020/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.