Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 5/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.40 |
| ▸ | RAD52 | P43351 | 2/20 | 0.39 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | FLT3 | P36888 | 2/20 | 0.36 |
| ▸ | MPO | P05164 | 2/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28054538 | 0.78 | TAAR1 (0.48) | NFE2L2TAAR1HTR2BSLC6A4 | |
| SCHEMBL10677990 | 0.73 | TAAR1 (0.50) | NFE2L2TAAR1FLT3 | |
| SCHEMBL23457281 | 0.72 | NFE2L2 (0.50) | NFE2L2 | |
| SCHEMBL28054812 | 0.71 | TAAR1 (0.42) | NFE2L2TAAR1HTR2BSLC6A4 | |
| SCHEMBL16957441 | 0.70 | NFE2L2 (0.47) | NFE2L2 | |
| SCHEMBL28054555 | 0.69 | TAAR1 (0.36) | TAAR1RAD52HTR2BMPOSLC6A4 | |
| SCHEMBL16951470 | 0.68 | NFE2L2 (0.46) | NFE2L2RIPK1 | |
| SCHEMBL16955968 | 0.68 | NFE2L2 (0.46) | NFE2L2 | |
| SCHEMBL16958585 | 0.68 | NFE2L2 (0.42) | NFE2L2RIPK1 | |
| SCHEMBL16954210 | 0.68 | NFE2L2 (0.42) | NFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105330595-A | Pyridine derivative and application thereof to mycobacterium resistance | NANJING MINGDE DRUG R & D CO LTD | 2016-02-17 | — | — | CN | disclosed |