SCHEMBL28054554

SCHEMBL28054554

COc1cccc(-c2nc(C)c3ccccc3n2)c1

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 12/20 0.74
CYP3A4 P08684 12/20 0.74
CYP2C9 P11712 6/20 0.74
CYP2B6 P20813 2/20 0.74
AHR P35869 2/20 0.74
NR1I3 Q14994 2/20 0.74
VDR P11473 1/20 0.74
CYP2D6 P10635 10/20 0.69
CYP2C19 P33261 7/20 0.69
MAPK1 P28482 6/20 0.69
USP2 O75604 6/20 0.69
CLK4 Q9HAZ1 5/20 0.69
ALOX15 P16050 5/20 0.69
HSD17B10 Q99714 4/20 0.69
MAPT P10636 2/20 0.66
ATM Q13315 1/20 0.66
TSHR P16473 8/20 0.65
LMNA P02545 5/20 0.65
MEN1 O00255 5/20 0.65
KMT2A Q03164 5/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27694078 0.84 CYP1A2 (0.72) CYP1A2CYP3A4CYP2C9CYP2B6AHR
SCHEMBL28196625 0.84 CYP1A2 (0.72) CYP1A2CYP3A4CYP2C9CYP2B6AHR
SCHEMBL24393204 0.84 AURKA (0.58) CYP1A2CYP3A4CYP2C9CYP2B6AHR
SCHEMBL16404287 0.83 CYP1A2 (0.68) CYP1A2CYP2C19MAPK1MAPTLMNA
SCHEMBL20233980 0.83 PDE10A (0.59) CYP1A2CYP3A4CYP2C9CYP2B6AHR
SCHEMBL26858214 0.82 KMT2A (0.56) CYP1A2CYP3A4CYP2C9CYP2B6AHR
SCHEMBL16037634 0.82 CYP1A2 (0.69) CYP1A2CYP3A4CYP2C9CYP2B6AHR
SCHEMBL17904147 0.81 NR1I3 (0.68) CYP1A2CYP3A4CYP2C9CYP2B6AHR
SCHEMBL29712524 0.81 CYP1A2 (0.67) CYP1A2CYP3A4CYP2C9CYP2B6AHR
SCHEMBL28315176 0.81 CYP1A2 (0.67) CYP1A2CYP3A4CYP2C9CYP2B6AHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105327703-B The preparation method of gold nano catalyst and the catalyst prod obtained and application 中国科学技术大学 2017-11-24 CN disclosed
CN-105327703-A Preparation method for gold nanometer catalyst, and obtained catalyst product and application thereof USTC UNIV SCIENCE TECH CN 2016-02-17 CN disclosed