Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.68 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.68 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.68 |
| ▸ | SYK | P43405 | 1/20 | 0.67 |
| ▸ | ABCG2 | Q9UNQ0 | 4/20 | 0.59 |
| ▸ | MAPT | P10636 | 4/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | TP53 | P04637 | 2/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.58 |
| ▸ | ABCC1 | P33527 | 2/20 | 0.54 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.54 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.54 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.54 |
| ▸ | KDM1A | O60341 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19169418 | 0.84 | PDE10A (0.60) | CYP1A2CYP1A1CYP1B1ABCG2MAPT | |
| SCHEMBL24393204 | 0.84 | AURKA (0.58) | CYP1A2CYP1A1CYP1B1ABCG2MAPT | |
| SCHEMBL422358 | 0.84 | PDE10A (0.61) | CYP1A2CYP1A1CYP1B1ABCG2MAPT | |
| SCHEMBL23743253 | 0.84 | MAPT (0.72) | CYP1A2CYP1A1CYP1B1SYKABCG2 | |
| SCHEMBL28054554 | 0.83 | CYP1A2 (0.74) | CYP1A2ABCG2MAPTALDH1A1MEN1 | |
| SCHEMBL19449104 | 0.83 | CYP1A2 (0.68) | CYP1A2CYP1A1CYP1B1ABCG2MAPT | |
| SCHEMBL13357329 | 0.83 | CYP1A1 (0.97) | CYP1A2CYP1A1CYP1B1SYKABCG2 | |
| SCHEMBL29592179 | 0.83 | CYP1A1 (0.97) | CYP1A2CYP1A1CYP1B1SYKABCG2 | |
| SCHEMBL16404325 | 0.83 | CYP1A2 (0.67) | CYP1A2CYP1A1CYP1B1SYKABCG2 | |
| SCHEMBL28147437 | 0.83 | ADORA2A (0.68) | CYP1A2CYP1A1CYP1B1SYKABCG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8936840-B2 | Retardation film, polarizing plate, liquid crystal display device, and compound | Konica Minolta, Inc. (JP) | 2015-01-20 | — | — | US | disclosed |
| US-8936840-B2 | Retardation film, polarizing plate, liquid crystal display device, and compound | Konica Minolta, Inc. (JP) | 2015-01-20 | — | — | US | disclosed |
| CN-102675222-B | Method for preparing multi-substituted quinazoline and heterocyclic pyrimidine derivative | UNIV TSINGHUA | 2014-11-26 | — | — | CN | disclosed |
| CN-102675223-B | Preparation method for polysubstitution quinazoline and heterocyclic ring pyrimidine derivative | UNIV TSINGHUA | 2014-08-27 | — | — | CN | disclosed |
| CN-102675223-A | Preparation method for polysubstitution quinazoline and heterocyclic ring pyrimidine derivative | UNIV TSINGHUA | 2012-09-19 | — | — | CN | disclosed |
| CN-102675222-A | Method for preparing multi-substituted quinazoline and heterocyclic pyrimidine derivative | UNIV TSINGHUA | 2012-09-19 | — | — | CN | disclosed |