Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | CTSA | P10619 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28054746 | 0.94 | ALOX15 (0.39) | — | |
| SCHEMBL28054858 | 0.93 | CTSA (0.34) | CTSA | |
| SCHEMBL28054890 | 0.93 | NPSR1 (0.35) | — | |
| SCHEMBL28054702 | 0.92 | — | — | |
| SCHEMBL28054830 | 0.92 | NPSR1 (0.34) | — | |
| SCHEMBL28054837 | 0.89 | — | — | |
| SCHEMBL28054847 | 0.89 | KMT2A (0.33) | — | |
| SCHEMBL28054846 | 0.85 | — | — | |
| SCHEMBL28054703 | 0.84 | NPSR1 (0.34) | CTSA | |
| SCHEMBL28054701 | 0.84 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105693771-A | Phosphonate compound containing pyrimidine ring as well as preparation method and application thereof | 华中师范大学 | 2016-06-22 | — | — | CN | disclosed |