Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | MAPT | P10636 | 6/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | MPI | P34949 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 3/20 | 0.42 |
| ▸ | THRA | P10827 | 2/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19460293 | 0.84 | KMT2A (0.44) | KMT2AALDH1A1MAPTLMNAMPI | |
| SCHEMBL17670064 | 0.82 | KMT2A (0.50) | KMT2AALDH1A1MAPTGLALMNA | |
| SCHEMBL28054865 | 0.77 | KMT2A (0.44) | KMT2AALDH1A1MAPTLMNAMPI | |
| SCHEMBL16212948 | 0.77 | EED (0.46) | KMT2AALDH1A1MAPTLMNAMPI | |
| SCHEMBL28054736 | 0.70 | EED (0.47) | KMT2AALDH1A1MAPTLMNAL3MBTL1 | |
| SCHEMBL16212834 | 0.70 | EED (0.59) | KMT2AALDH1A1MAPTGLALMNA | |
| SCHEMBL16212833 | 0.70 | EED (0.59) | KMT2AALDH1A1MAPTGLALMNA | |
| SCHEMBL16212832 | 0.70 | EED (0.59) | KMT2AALDH1A1MAPTGLALMNA | |
| SCHEMBL9512833 | 0.69 | ALDH1A1 (0.84) | KMT2AALDH1A1MAPTLMNAMPI | |
| SCHEMBL12123790 | 0.69 | ALDH1A1 (0.73) | KMT2AALDH1A1MAPTLMNAMPI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105308038-A | Enhancer of zeste homolog 2 inhibitors | GLAXOSMITHKLINE IP NO 2 LTD | 2016-02-03 | — | — | CN | disclosed |