Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A known ✓ | P08908 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | NSD2 | O96028 | 1/20 | 0.50 |
| ▸ | EGFR | P00533 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 3/20 | 0.36 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.35 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.35 |
| ▸ | HNF4A | P41235 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7915840 | 0.96 | ALDH1A1 (0.53) | ALDH1A1MAPTMAPK1L3MBTL1NSD2 | |
| SCHEMBL6724502 | 0.84 | ALDH1A1 (0.40) | ALDH1A1MAPTMAPK1L3MBTL1NSD2 | |
| SCHEMBL28285937 | 0.83 | MAPT (0.50) | ALDH1A1MAPTMAPK1L3MBTL1NSD2 | |
| SCHEMBL29433183 | 0.79 | ALDH1A1 (0.45) | ALDH1A1MAPTMAPK1L3MBTL1NSD2 | |
| SCHEMBL1254512 | 0.79 | ALDH1A1 (0.45) | ALDH1A1MAPTMAPK1L3MBTL1NSD2 | |
| Phosphine SCHEMBL27890176 | 0.78 | KCNN4 (0.42) | ALDH1A1MAPTMAPK1L3MBTL1NSD2 | |
| SCHEMBL27517786 | 0.77 | ALDH1A1 (0.44) | ALDH1A1MAPTMAPK1L3MBTL1NSD2 | |
| SCHEMBL30763243 | 0.77 | ALDH1A1 (0.44) | ALDH1A1MAPTMAPK1L3MBTL1NSD2 | |
| SCHEMBL27516508 | 0.77 | ALDH1A1 (0.44) | ALDH1A1MAPTMAPK1L3MBTL1NSD2 | |
| Hydrochloric Acid SCHEMBL2866856 | 0.77 | ALDH1A1 (0.44) | ALDH1A1MAPTMAPK1L3MBTL1NSD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105400403-A | Colored coating and artificial leather | MILLIKEN & CO | 2016-03-16 | — | — | CN | disclosed |
| CN-105400404-A | Colored coating and artificial leather comprising a colorant complex | MILLIKEN & CO | 2016-03-16 | — | — | CN | disclosed |