Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR2 | O43614 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 3/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | APLNR | P35414 | 1/20 | 0.33 |
| ▸ | NPFFR1 | Q9GZQ6 | 1/20 | 0.32 |
| ▸ | NPFFR2 | Q9Y5X5 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28055196 | 0.86 | HCRTR2 (0.40) | HCRTR2EPHX1TDP1MEN1KMT2A | |
| SCHEMBL5962444 | 0.84 | EPHX1 (0.41) | HCRTR2EPHX1TDP1MEN1KMT2A | |
| SCHEMBL25970649 | 0.80 | HCRTR2 (0.46) | HCRTR2EPHX1TDP1MEN1KMT2A | |
| SCHEMBL29541374 | 0.80 | HCRTR2 (0.36) | HCRTR2EPHX1TDP1MEN1KMT2A | |
| SCHEMBL20567755 | 0.80 | HCRTR2 (0.36) | HCRTR2EPHX1TDP1MEN1KMT2A | |
| SCHEMBL23477736 | 0.79 | HCRTR2 (0.38) | HCRTR2EPHX1TDP1MEN1KMT2A | |
| SCHEMBL25785532 | 0.79 | HCRTR2 (0.45) | HCRTR2EPHX1TDP1MEN1KMT2A | |
| SCHEMBL508325 | 0.79 | HCRTR2 (0.42) | HCRTR2EPHX1TDP1MEN1KMT2A | |
| SCHEMBL31446944 | 0.78 | HCRTR2 (0.39) | HCRTR2EPHX1TDP1MEN1KMT2A | |
| SCHEMBL22945019 | 0.78 | EPHX1 (0.39) | HCRTR2EPHX1TDP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103214484-B | Pyrrolo-[2,3-b] pyridine replaced as the heteroaryl of Janus inhibitors of kinases and pyrrolo-[2,3-b] pyrimidine | 因塞特控股公司 | 2016-07-06 | — | — | CN | disclosed |