SCHEMBL28055322

SCHEMBL28055322

[Cu].c1cc(CCCc2ccncc2)ccn1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HRH1 P35367 2/20 0.62
LOXL2 Q9Y4K0 2/20 0.59
HRH3 Q9Y5N1 3/20 0.57
HRH4 Q9H3N8 2/20 0.57
NAAA Q02083 1/20 0.50
CYP1A2 P05177 5/20 0.48
CYP3A4 P08684 5/20 0.48
CYP2D6 P10635 4/20 0.48
CYP2C9 P11712 4/20 0.48
CYP2C19 P33261 4/20 0.48
ALDH1A1 P00352 1/20 0.48
HSD17B10 Q99714 1/20 0.48
TDP1 Q9NUW8 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
HIF1A Q16665 1/20 0.45
NPC1 O15118 1/20 0.44
KMT2A Q03164 1/20 0.44
LMNA P02545 1/20 0.41
TSHR P16473 1/20 0.41
HTT P42858 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL351920 0.97 HRH1 (0.65) HRH1LOXL2HRH3HRH4NAAA
SCHEMBL31673871 0.94 HRH1 (0.62) HRH1LOXL2HRH3HRH4NAAA
SCHEMBL726645 0.91 HRH1 (0.73) HRH1LOXL2HRH3HRH4NAAA
SCHEMBL725306 0.88 HRH1 (0.77) HRH1LOXL2HRH3HRH4NAAA
SCHEMBL4413800 0.88 HRH1 (0.77) HRH1LOXL2HRH3HRH4NAAA
SCHEMBL2841394 0.88 HRH1 (0.77) HRH1LOXL2HRH3HRH4NAAA
SCHEMBL123539 0.87 CYP1A2 (0.61) HRH1LOXL2HRH3HRH4CYP1A2
Pyridine SCHEMBL19285795 0.87 HRH1 (0.56) HRH1LOXL2HRH3HRH4NAAA
Hydrochloric Acid SCHEMBL6419195 0.85 CYP1A2 (0.59) HRH1LOXL2HRH3HRH4CYP1A2
Iodide SCHEMBL8083284 0.85 CYP1A2 (0.59) HRH1LOXL2HRH3HRH4CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105315302-A Non-hydrous 1,3-di(4-pyridyl) propane copper o-chloromandelate ferroelectric functional material and preparation method therefor UNIV NINGBO 2016-02-10 CN disclosed
CN-105315302-A Non-hydrous 1,3-di(4-pyridyl) propane copper o-chloromandelate ferroelectric functional material and preparation method therefor UNIV NINGBO 2016-02-10 CN disclosed