Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 1/20 | 0.64 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28055381 | 1.00 | DDB1 (0.64) | DDB1CRBNALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL5319955 | 0.80 | DDB1 (0.51) | DDB1CRBNALDH1A1 | |
| SCHEMBL19586342 | 0.78 | CRBN (1.00) | DDB1CRBNALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL28355627 | 0.78 | DDB1 (0.49) | DDB1CRBNALDH1A1KMT2ACYP3A4 | |
| SCHEMBL2125064 | 0.77 | DDB1 (0.54) | DDB1CRBNALDH1A1 | |
| SCHEMBL4962412 | 0.76 | DDB1 (0.56) | DDB1CRBNALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL14124937 | 0.76 | DDB1 (0.56) | DDB1CRBNALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL17816474 | 0.76 | DDB1 (0.50) | DDB1CRBNALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL14537683 | 0.76 | DDB1 (0.50) | DDB1CRBNALDH1A1 | |
| SCHEMBL1504008 | 0.76 | DDB1 (0.59) | DDB1CRBNALDH1A1MAPK1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105521826-A | Zirconium catalyst and method for preparing chiral alpha-hydroxy-beta-keto ester compound by use of zirconium catalyst | UNIV DALIAN TECH | 2016-04-27 | — | — | CN | disclosed |