Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 1/20 | 0.51 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3696556 | 0.81 | DDB1 (0.49) | DDB1CRBN | |
| SCHEMBL2125064 | 0.81 | DDB1 (0.54) | DDB1CRBNALDH1A1 | |
| SCHEMBL28055381 | 0.80 | DDB1 (0.64) | DDB1CRBNALDH1A1 | |
| SCHEMBL28055405 | 0.80 | DDB1 (0.64) | DDB1CRBNALDH1A1 | |
| SCHEMBL14537683 | 0.80 | DDB1 (0.50) | DDB1CRBNALDH1A1 | |
| SCHEMBL28351712 | 0.76 | DDB1 (0.47) | DDB1CRBNALDH1A1 | |
| SCHEMBL28355472 | 0.76 | DDB1 (0.47) | DDB1CRBNALDH1A1 | |
| SCHEMBL7228727 | 0.74 | DDB1 (0.52) | DDB1CRBNALDH1A1 | |
| SCHEMBL4962412 | 0.74 | DDB1 (0.56) | DDB1CRBNALDH1A1 | |
| SCHEMBL23847125 | 0.73 | DDB1 (0.51) | DDB1CRBNALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007103719-A2 | MODULATORS OF 11-β HYDROXYL STEROID DEHYDROGENASE TYPE 1, PHARMACEUTICAL COMPOSITIONS THEREOF, AND METHODS OF USING THE SAME | INCYTE CORPORATION (US) | 2007-09-13 | — | — | WO | disclosed |