Iodomethane

Iodomethane

SCHEMBL28055463

CI.COc1ccc(F)c(F)c1

nearest known ligand 0.47

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.47
CYP1A1 P04798 1/20 0.47
CYP1B1 Q16678 1/20 0.47
CA12 O43570 2/20 0.46
CA1 P00915 2/20 0.46
CA2 P00918 2/20 0.46
CA7 P43166 2/20 0.46
CA9 Q16790 2/20 0.46
CA14 Q9ULX7 2/20 0.46
CPS1 P31327 3/20 0.44
MAPT P10636 2/20 0.44
MEN1 O00255 1/20 0.44
GAA P10253 1/20 0.44
KMT2A Q03164 1/20 0.44
CYP2A6 P11509 1/20 0.43
TAAR1 Q96RJ0 1/20 0.42
SLC6A2 P23975 1/20 0.42
SLC6A4 P31645 1/20 0.42
SLC6A3 Q01959 1/20 0.42
NFE2L2 Q16236 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL254529 0.95 CA12 (0.50) CYP1A2CYP1A1CYP1B1CA12CA1
SCHEMBL29513208 0.95 CA12 (0.50) CYP1A2CYP1A1CYP1B1CA12CA1
SCHEMBL27541994 0.85 CPS1 (0.45) CYP1A2CYP1A1CYP1B1CA12CA1
SCHEMBL27699833 0.83 SOS1 (0.47) CYP1A2CYP1A1CYP1B1CPS1MAPT
Tetrahydrofuran SCHEMBL28130288 0.80 CPS1 (0.42) CYP1A2CYP1A1CYP1B1CA12CA1
SCHEMBL29509707 0.79 CA12 (0.43) CYP1A2CYP1A1CYP1B1CA12CA1
SCHEMBL15718550 0.79 CA12 (0.43) CYP1A2CYP1A1CYP1B1CA12CA1
SCHEMBL1510025 0.79 CYP1A2 (0.46) CYP1A2CYP1A1CYP1B1CA12CA1
SCHEMBL10340365 0.78 AMY1A (0.50) CYP1A2CYP1A1CYP1B1CA12CA1
SCHEMBL3614957 0.77 CYP11B1 (0.53) CA12CA1CA2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105523904-A Method for preparing 3,4-difluoroanisole TIANJIN HEOWNS BIOCHEMISTRY TECH CO LTD 2016-04-27 CN disclosed