Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 6/20 | 0.37 |
| ▸ | RAB9A | P51151 | 5/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | CASP1 | P29466 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3698024 | 0.84 | ALDH1A1 (0.41) | KDM4EALDH1A1GAAHPGDSMN1; SMN2 | |
| SCHEMBL9018825 | 0.82 | PTPN1 (0.42) | KDM4ELMNARXFP1IDO1ALDH1A1 | |
| SCHEMBL29354014 | 0.82 | ALDH1A1 (0.50) | KDM4EALDH1A1GAAHPGDSMN1; SMN2 | |
| SCHEMBL2871930 | 0.82 | ALDH1A1 (0.50) | KDM4EALDH1A1GAAHPGDSMN1; SMN2 | |
| SCHEMBL537002 | 0.80 | ALDH1A1 (0.52) | KDM4EALDH1A1GAAHPGDSMN1; SMN2 | |
| SCHEMBL29538643 | 0.80 | ALDH1A1 (0.48) | KDM4EALDH1A1GAAHPGDSMN1; SMN2 | |
| SCHEMBL27506937 | 0.80 | ALDH1A1 (0.48) | KDM4EALDH1A1GAAHPGDSMN1; SMN2 | |
| SCHEMBL5890646 | 0.77 | KDM4E (0.52) | KDM4ELMNARXFP1IDO1ALDH1A1 | |
| SCHEMBL31087243 | 0.77 | KDM4E (0.52) | KDM4ELMNARXFP1IDO1ALDH1A1 | |
| SCHEMBL19802370 | 0.76 | ALDH1A1 (0.47) | KDM4EALDH1A1GAAHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103456884-B | Organic electroluminescence device | MERCK PATENT GMBH (DE) | 2016-03-09 | — | — | CN | disclosed |
| CN-103456884-A | Organic electroluminescent device | MERCK PATENT GMBH | 2013-12-18 | — | — | CN | disclosed |