SCHEMBL28055677

SCHEMBL28055677

COC(=O)C(C)=CCCc1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.46
GPR52 Q9Y2T5 8/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
NPC1 O15118 1/20 0.44
RAB9A P51151 1/20 0.44
GRIK1 P39086 1/20 0.44
HPGD P15428 1/20 0.44
TRPV1 Q8NER1 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3084763 0.91 TRPV1 (0.52) ALDH1A1GPR52TRPV1
SCHEMBL3084764 0.91 TRPV1 (0.52) ALDH1A1GPR52TRPV1
SCHEMBL3084761 0.91 TRPV1 (0.52) ALDH1A1GPR52TRPV1
SCHEMBL3292425 0.85 GRIK1 (0.47) ALDH1A1GPR52SMN1; SMN2NPC1RAB9A
SCHEMBL28187044 0.84 ALDH1A1 (0.54) ALDH1A1GRIK1TRPV1
SCHEMBL28186332 0.84 HCAR2 (0.50) ALDH1A1SMN1; SMN2NPC1RAB9AGRIK1
SCHEMBL28199414 0.84 SMN1; SMN2 (0.49) ALDH1A1GPR52SMN1; SMN2GRIK1TRPV1
SCHEMBL24425868 0.83 ALDH1A1 (0.43) ALDH1A1SMN1; SMN2NPC1RAB9AHPGD
SCHEMBL715040 0.83 ALDH1A1 (0.43) ALDH1A1SMN1; SMN2NPC1RAB9AHPGD
SCHEMBL19656184 0.83 TSHR (0.49) ALDH1A1GPR52SMN1; SMN2NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105585657-B A kind of pour depressant for lubricating oil and preparation method thereof 中国石油化工股份有限公司 2018-03-20 CN disclosed
CN-105524209-B Acrylate based copolymer and its application and pour depressant for lubricating oil and preparation method thereof 中国石油化工股份有限公司 2017-09-29 CN disclosed
CN-105585657-A Lubricant oil pour point depressant and preparation method thereof CHINA PETROLEUM & CHEM CORP 2016-05-18 CN disclosed
CN-105524209-A Acrylate copolymer, use of acrylate copolymer, lubricating oil pour-point depressant and preparation method of lubricating oil pour-point depressant CHINA PETROLEUM & CHEM CORP 2016-04-27 CN disclosed