Phosphine

Phosphine

SCHEMBL28055753

C=C(CC(=O)OCC1CO1)C(=O)OCC1CO1.P

nearest known ligand 0.61

Full drug profile on Sugi Atlas →

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.61
TP53 P04637 1/20 0.43
CYP3A4 P08684 1/20 0.43
MGLL Q99685 4/20 0.41
LMNA P02545 1/20 0.37
POLB P06746 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL221571 0.98 ALDH1A1 (0.62) ALDH1A1TP53CYP3A4MGLLLMNA
Ether SCHEMBL11860765 0.89 ALDH1A1 (0.57) ALDH1A1TP53CYP3A4MGLL
SCHEMBL4338206 0.88 ALDH1A1 (0.59) ALDH1A1TP53CYP3A4MGLLLMNA
SCHEMBL4897393 0.88 ALDH1A1 (0.64) ALDH1A1TP53CYP3A4MGLL
Glycerin SCHEMBL28154727 0.88 ALDH1A1 (0.51) ALDH1A1TP53CYP3A4MGLL
SCHEMBL221572 0.86 ALDH1A1 (0.61) ALDH1A1TP53CYP3A4MGLL
SCHEMBL6265408 0.85 ALDH1A1 (0.49) ALDH1A1TP53CYP3A4MGLL
Methane SCHEMBL5161235 0.84 ALDH1A1 (0.59) ALDH1A1TP53CYP3A4MGLL
SCHEMBL20503788 0.84 ALDH1A1 (0.69) ALDH1A1TP53CYP3A4MGLL
SCHEMBL8686351 0.84 ALDH1A1 (0.59) ALDH1A1TP53CYP3A4MGLLLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103965245-B A kind of containing phosphorus bio-based diacid 2-glycidyl ester and its preparation method and application 中国科学院宁波材料技术与工程研究所 2016-06-08 CN disclosed
CN-103965246-B A kind of phosphorous bio-based diacid diallyl ester and its preparation method and application NINGBO INSTITUTE OF MATERIALS TECHNOLOGY & ENGINEERING, CHINESE ACADEMY OF SCIENCES (CN) 2016-04-20 CN disclosed