Naphthalene

Naphthalene

SCHEMBL28055820

CC[Si](C)(Cl)Cl.c1ccc2ccccc2c1

nearest known ligand 0.44

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 6/20 0.44
ALOX12 P18054 1/20 0.44
CYP1A2 P05177 4/20 0.41
TDP1 Q9NUW8 2/20 0.35
TP53 P04637 1/20 0.33
ELANE P08246 1/20 0.32
ALDH1A1 P00352 2/20 0.32
HPGD P15428 2/20 0.32
KDM4E B2RXH2 1/20 0.32
GAA P10253 1/20 0.32
MAPT P10636 2/20 0.32
GLA P06280 1/20 0.32
ACHE P22303 1/20 0.32
HTT P42858 1/20 0.31
DDAH1 O94760 1/20 0.31
MEN1 O00255 1/20 0.31
RAB9A P51151 1/20 0.31
KMT2A Q03164 1/20 0.31
ATM Q13315 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Naphthalene SCHEMBL5081662 0.82 CYP2A6 (0.57) CYP2A6ALOX12CYP1A2TDP1ALDH1A1
Biphenyl SCHEMBL8342873 0.81 ALDH1A1 (0.47) CYP1A2TP53ALDH1A1HPGDKDM4E
Naphthalene SCHEMBL28535823 0.77 CYP2A6 (0.38) CYP2A6ALOX12CYP1A2TDP1ELANE
Anthracene SCHEMBL3794553 0.76 CYP2A6 (0.44) CYP2A6ALOX12CYP1A2TDP1ALDH1A1
Naphthalene SCHEMBL27686354 0.76 CYP2A6 (0.57) CYP2A6ALOX12CYP1A2TDP1TP53
Naphthalene SCHEMBL28055828 0.75 CYP2A6 (0.36) CYP2A6ALOX12CYP1A2TDP1TP53
Naphthalene SCHEMBL11774251 0.75 CYP2A6 (0.67) CYP2A6ALOX12CYP1A2TDP1TP53
SCHEMBL301942 0.74
Naphthalene SCHEMBL1538234 0.72 CYP2A6 (0.61) CYP2A6ALOX12CYP1A2TDP1TP53
Naphthalene SCHEMBL1573914 0.71 CYP2A6 (0.73) CYP2A6ALOX12CYP1A2TDP1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105418927-A Low dielectric constant material film and preparation method thereof SHANGHAI ADVANCED RES INST CAS 2016-03-23 CN disclosed
CN-105418926-A Fluorine-containing naphthalene ethyl silicon resin, preparation method and applications thereof SHANGHAI ADVANCED RES INST CAS 2016-03-23 CN disclosed