Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | BACE1 | P56817 | 6/20 | 0.41 |
| ▸ | TLR8 | Q9NR97 | 6/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | IKBKB | O14920 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23405034 | 0.75 | TLR8 (0.45) | KDM4EALDH1A1GAABACE1TLR8 | |
| SCHEMBL24092011 | 0.75 | TLR8 (0.47) | KDM4EALDH1A1GAATLR8RAB9A | |
| SCHEMBL28109304 | 0.72 | GAA (0.37) | KDM4EGAAADORA2AADORA1SMN1; SMN2 | |
| SCHEMBL4513395 | 0.71 | RAB9A (0.36) | KDM4EALDH1A1GAARAB9AADORA2A | |
| SCHEMBL28672075 | 0.70 | TDP1 (0.42) | KDM4EALDH1A1GAARAB9ASMN1; SMN2 | |
| SCHEMBL30195952 | 0.70 | TDP1 (0.42) | KDM4EALDH1A1GAARAB9ASMN1; SMN2 | |
| SCHEMBL18081040 | 0.69 | PBRM1 (0.52) | IKBKB | |
| SCHEMBL18081119 | 0.69 | PBRM1 (0.52) | IKBKB | |
| SCHEMBL18038849 | 0.69 | PBRM1 (0.52) | IKBKB | |
| SCHEMBL2032834 | 0.69 | SLC6A4 (0.49) | KDM4EALDH1A1RAB9ASMN1; SMN2IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105733559-A | Oxalyl aminoquinoline derivative fluorescent molecular probe and preparation method and application thereof | 齐齐哈尔大学 | 2016-07-06 | — | — | CN | disclosed |
| CN-105733559-A | Oxalyl aminoquinoline derivative fluorescent molecular probe and preparation method and application thereof | 齐齐哈尔大学 | 2016-07-06 | — | — | CN | disclosed |