SCHEMBL28056025

SCHEMBL28056025

c1ccc(-c2cccc([Si](c3ccccc3)(c3ccccc3)c3ccccc3)c2[Si](c2ccccc2)(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.35
HSD17B10 Q99714 3/20 0.35
MAPK1 P28482 3/20 0.35
HPGD P15428 2/20 0.35
BCL2L1 Q07817 1/20 0.35
CYP2A6 P11509 1/20 0.35
GPR55 Q9Y2T6 1/20 0.35
RAB9A P51151 2/20 0.34
NPC1 O15118 1/20 0.34
METAP2 P50579 1/20 0.34
TNF P01375 1/20 0.34
MAP4K4 O95819 1/20 0.33
CSF1R P07333 1/20 0.33
FGFR1 P11362 1/20 0.33
PDGFRA P16234 1/20 0.33
LTK P29376 1/20 0.33
KDR P35968 1/20 0.33
MAPK8 P45983 1/20 0.33
CSNK1A1 P48729 1/20 0.33
LIMK1 P53667 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16115423 0.83 ALDH1A1 (0.41) ALDH1A1HSD17B10MAPK1HPGDBCL2L1
SCHEMBL30332661 0.83 ALDH1A1 (0.41) ALDH1A1HSD17B10MAPK1HPGDBCL2L1
SCHEMBL31175994 0.80 ALDH1A1 (0.37) ALDH1A1HSD17B10MAPK1HPGDBCL2L1
SCHEMBL16115916 0.79 ALDH1A1 (0.39) ALDH1A1HSD17B10MAPK1HPGDBCL2L1
SCHEMBL3889982 0.79 ALDH1A1 (0.41) ALDH1A1HSD17B10MAPK1HPGDBCL2L1
SCHEMBL9319707 0.79 ALDH1A1 (0.41) ALDH1A1HSD17B10MAPK1HPGDBCL2L1
SCHEMBL28864155 0.78 ALDH1A1 (0.43) ALDH1A1HSD17B10MAPK1HPGDBCL2L1
SCHEMBL31591138 0.78 ALDH1A1 (0.36) ALDH1A1HSD17B10MAPK1HPGDBCL2L1
SCHEMBL29036363 0.78 CYP2A6 (0.54) ALDH1A1HSD17B10MAPK1HPGDBCL2L1
SCHEMBL13295274 0.75 NPC1 (0.33) ALDH1A1HSD17B10MAPK1GPR55RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105392863-A Composition and light-emitting element using the same SUMITOMO CHEMICAL CO 2016-03-09 CN disclosed