6Beta-Hydroxytestosterone

6Beta-Hydroxytestosterone

SCHEMBL28056047

CC12CCC(=O)C=C1C(O)CC1C2CCC2(C)C(O)CCC12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 3/20 1.00
CYP19A1 P11511 12/20 0.80
SHBG P04278 3/20 0.80
AR P10275 5/20 0.79
LMNA P02545 3/20 0.67
HSD17B10 Q99714 3/20 0.67
SERPINA6 P08185 3/20 0.67
NR3C1 P04150 2/20 0.67
PGR P06401 2/20 0.67
TSHR P16473 2/20 0.67
SNCA P37840 2/20 0.67
CACNA1C Q13936 2/20 0.67
CYP51A1 Q16850 2/20 0.67
GPBAR1 Q8TDU6 2/20 0.67
SIGMAR1 Q99720 2/20 0.67
MAPT P10636 1/20 0.67
MAPK1 P28482 1/20 0.67
OR51E2 Q9H255 1/20 0.67
ESR2 Q92731 2/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
6Beta-Hydroxytestosterone SCHEMBL135030 1.00 CYP3A4 (1.00) CYP3A4CYP19A1SHBGARLMNA
6Beta-Hydroxytestosterone SCHEMBL4122472 1.00 CYP3A4 (1.00) CYP3A4CYP19A1SHBGARLMNA
6Beta-Hydroxytestosterone SCHEMBL3278189 1.00 CYP3A4 (1.00) CYP3A4CYP19A1SHBGARLMNA
6Beta-Hydroxytestosterone SCHEMBL14067596 1.00 CYP3A4 (1.00) CYP3A4CYP19A1SHBGARLMNA
6Beta-Hydroxytestosterone SCHEMBL127408 1.00 CYP3A4 (1.00) CYP3A4CYP19A1SHBGARLMNA
6Beta-Hydroxytestosterone SCHEMBL13752809 1.00 CYP3A4 (1.00) CYP3A4CYP19A1SHBGARLMNA
SCHEMBL11524096 0.89 CYP19A1 (1.00) CYP3A4CYP19A1SHBGARLMNA
SCHEMBL6006777 0.89 CYP19A1 (1.00) CYP3A4CYP19A1SHBGARLMNA
SCHEMBL10273241 0.89 CYP19A1 (1.00) CYP3A4CYP19A1SHBGARLMNA
SCHEMBL5021333 0.89 CYP19A1 (1.00) CYP3A4CYP19A1SHBGARLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105851049-A Insecticide for controlling Phenacoccus solenopsis Tinsley 烟台图文马克化工科技有限公司 2016-08-17 CN disclosed
CN-105735132-A Building method of circular arch bridge 张译元 2016-07-06 CN disclosed