Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.58 |
| ▸ | NPC1 | O15118 | 3/20 | 0.58 |
| ▸ | RAB9A | P51151 | 3/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.58 |
| ▸ | TP53 | P04637 | 2/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | SCN4A | P35499 | 1/20 | 0.48 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.48 |
| ▸ | FSCN1 | Q16658 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12211789 | 0.87 | NPC1 (0.56) | MAPTNPC1RAB9ASMN1; SMN2HTT | |
| SCHEMBL18003453 | 0.85 | MAPT (0.62) | MAPTNPC1RAB9ASMN1; SMN2HTT | |
| SCHEMBL11324517 | 0.83 | AKR1B1 (0.60) | MAPTNPC1RAB9ASMN1; SMN2HTT | |
| SCHEMBL202482 | 0.82 | NPC1 (0.62) | MAPTNPC1RAB9ASMN1; SMN2HTT | |
| SCHEMBL12211786 | 0.79 | NPC1 (0.53) | MAPTNPC1RAB9ASMN1; SMN2HTT | |
| SCHEMBL28320559 | 0.79 | NPC1 (0.56) | MAPTNPC1RAB9ASMN1; SMN2HTT | |
| SCHEMBL12210611 | 0.79 | LIPG (0.61) | — | |
| SCHEMBL11100119 | 0.78 | NPC1 (0.58) | MAPTNPC1RAB9ASMN1; SMN2HTT | |
| SCHEMBL12211792 | 0.78 | LIPG (0.74) | MAPTNPC1RAB9ASMN1; SMN2HTT | |
| SCHEMBL1612659 | 0.78 | SMN1; SMN2 (0.67) | MAPTNPC1RAB9ASMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105408325-A | Cyanotriazole compounds | OTSUKA PHARMA CO LTD | 2016-03-16 | — | — | CN | disclosed |