SCHEMBL28056292

SCHEMBL28056292

O=C(O)c1ccccc1[C@@H](O)CCCCO

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.44
KMT2A Q03164 2/20 0.44
GAA P10253 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
ALOX15 P16050 1/20 0.43
HTT P42858 1/20 0.43
MAPT P10636 1/20 0.41
HDAC8 Q9BY41 1/20 0.41
KDM4E B2RXH2 4/20 0.41
TAAR1 Q96RJ0 1/20 0.41
FOLH1 Q04609 3/20 0.39
CA12 O43570 1/20 0.38
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
HMGB1 P09429 1/20 0.38
HPGD P15428 1/20 0.38
CA4 P22748 1/20 0.38
CA6 P23280 1/20 0.38
CA7 P43166 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28689312 0.95 ALDH1A1 (0.45) ALDH1A1KMT2AGAATDP1ALOX15
SCHEMBL4080822 0.89 ALDH1A1 (0.46) ALDH1A1KMT2AGAATDP1ALOX15
SCHEMBL4577215 0.84 HTT (0.36) ALDH1A1KMT2AGAATDP1ALOX15
SCHEMBL23521291 0.83 KMT2A (0.50) ALDH1A1KMT2AGAATDP1ALOX15
SCHEMBL1935639 0.83 KMT2A (0.50) ALDH1A1KMT2AGAATDP1ALOX15
SCHEMBL23521275 0.83 KMT2A (0.50) ALDH1A1KMT2AGAATDP1ALOX15
SCHEMBL29360777 0.83 KMT2A (0.50) ALDH1A1KMT2AGAATDP1ALOX15
SCHEMBL29869129 0.83 KMT2A (0.50) ALDH1A1KMT2AGAATDP1ALOX15
SCHEMBL11367881 0.82 ALDH1A1 (0.50) ALDH1A1KMT2AGAATDP1ALOX15
Potassium SCHEMBL31438078 0.81 KMT2A (0.49) ALDH1A1KMT2AGAATDP1ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105523918-A Novel compounds and applications thereof MI WENJUN 2016-04-27 CN disclosed
CN-105503584-A Novel compound and applications thereof MI WENJUN 2016-04-20 CN disclosed