Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | IDO1 | P14902 | 1/20 | 0.52 |
| ▸ | AGXT | P21549 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL794 | 0.97 | — | — | |
| Ammonia Solution, Strong SCHEMBL7706243 | 0.94 | TSHR (0.57) | TSHRIDO1AGXTALDH1A1MAOB | |
| SCHEMBL27308458 | 0.94 | TSHR (0.57) | TSHRIDO1AGXTALDH1A1MAOB | |
| SCHEMBL28732564 | 0.94 | TSHR (0.57) | TSHRIDO1AGXTALDH1A1MAOB | |
| Hydrochloric Acid SCHEMBL9981027 | 0.94 | TSHR (0.57) | TSHRIDO1AGXTALDH1A1MAOB | |
| Ethylene SCHEMBL27779295 | 0.92 | TSHR (0.55) | TSHRIDO1AGXTALDH1A1MAOB | |
| SCHEMBL2340242 | 0.87 | TSHR (0.50) | TSHRIDO1AGXTALDH1A1MAOB | |
| O-Xylene SCHEMBL6552474 | 0.87 | TSHR (0.50) | TSHRIDO1AGXTALDH1A1MAOB | |
| SCHEMBL1903758 | 0.87 | TSHR (0.50) | TSHRIDO1AGXTALDH1A1MAOB | |
| SCHEMBL13378281 | 0.87 | MAOA (0.50) | TSHRIDO1MAOBTDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102803229-B | Insecticidal compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2016-03-16 | — | — | CN | disclosed |
| CN-105377816-A | Pyridine-2-carboxamides as nematocides | SYNGENTA PARTICIPATIONS AG | 2016-03-02 | — | — | CN | disclosed |