Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | PTPRC | P08575 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27922948 | 0.84 | ALDH1A1 (0.58) | MAPK1ALDH1A1PTPRCHDAC4HDAC2 | |
| SCHEMBL27578855 | 0.81 | ALDH1A1 (0.56) | MAPK1ALDH1A1HDAC4HDAC2HDAC8 | |
| SCHEMBL29168515 | 0.80 | ALDH1A1 (0.64) | MAPK1ALDH1A1PTPRCLMNAMAPT | |
| SCHEMBL706912 | 0.80 | ALDH1A1 (0.48) | MAPK1ALDH1A1PTPRCLMNAMAPT | |
| SCHEMBL28056373 | 0.80 | ALDH1A1 (0.43) | ALDH1A1MEN1KMT2AMAOBMGLL | |
| SCHEMBL28056370 | 0.79 | ALDH1A1 (0.48) | MAPK1ALDH1A1PTPRCLMNAMAPT | |
| SCHEMBL27988868 | 0.76 | HDAC4 (0.35) | PTPRCHDAC4HDAC2HDAC8HDAC6 | |
| SCHEMBL24117506 | 0.75 | ALDH1A1 (0.44) | MAPK1ALDH1A1HDAC4HDAC2HDAC8 | |
| SCHEMBL28789264 | 0.74 | ALDH1A1 (0.52) | MAPK1ALDH1A1PTPRCMAPTHTT | |
| SCHEMBL24972613 | 0.74 | CYP2A6 (0.52) | MAPK1ALDH1A1PTPRCLMNASLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105504186-A | Preparing method and application of 3,4-bi(4-cyanophenyl)-2,5-diphenyl phenyl grafted polysiloxane | UNIV SHANDONG | 2016-04-20 | — | — | CN | claimed |
| CN-105504186-A | Preparing method and application of 3,4-bi(4-cyanophenyl)-2,5-diphenyl phenyl grafted polysiloxane | UNIV SHANDONG | 2016-04-20 | — | — | CN | disclosed |