SCHEMBL28056818

SCHEMBL28056818

C=Cc1ccccc1[SiH3].[Ce]

nearest known ligand 0.50

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.50
TSHR P16473 2/20 0.39
MEN1 O00255 1/20 0.35
LMNA P02545 1/20 0.35
THRB P10828 1/20 0.35
BLM P54132 1/20 0.35
KMT2A Q03164 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
NFE2L2 Q16236 1/20 0.31
HPGD P15428 2/20 0.31
MAPK1 P28482 1/20 0.31
HSD17B10 Q99714 1/20 0.31
HDAC8 Q9BY41 1/20 0.30
HTT P42858 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31448634 0.97
SCHEMBL141147 0.97
Hydrochloric Acid SCHEMBL27425510 0.94 ALDH1A1 (0.50) ALDH1A1TSHRMEN1LMNATHRB
SCHEMBL8072803 0.79 ALDH1A1 (0.41) ALDH1A1TSHR
SCHEMBL29405187 0.78 ALDH1A1 (0.63) ALDH1A1TSHRMEN1LMNATHRB
SCHEMBL473080 0.78 ALDH1A1 (0.63) ALDH1A1TSHRMEN1LMNATHRB
SCHEMBL7638 0.78 ALDH1A1 (0.63) ALDH1A1TSHRMEN1LMNATHRB
SCHEMBL1765862 0.77 ALDH1A1 (0.39) ALDH1A1
SCHEMBL27804483 0.77 ALDH1A1 (0.62) ALDH1A1TSHRMEN1LMNATHRB
SCHEMBL9562250 0.76 ALDH1A1 (0.60) ALDH1A1TSHRMEN1LMNATHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105518077-A Curable silicon composition, cured product thereof, and optical semiconductor device DOW CORNING TORAY CO LTD 2016-04-20 CN disclosed