Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 3/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.32 |
| ▸ | KDM5A | P29375 | 1/20 | 0.30 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.30 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7026717 | 0.98 | CYP19A1 (0.35) | CYP19A1HDAC1KDM5AKDM4CKDM5B | |
| SCHEMBL27711036 | 0.85 | KCNH2 (0.44) | CYP19A1HDAC1KDM5AKDM4CKDM5B | |
| SCHEMBL292762 | 0.85 | HDAC1 (0.31) | HDAC1 | |
| SCHEMBL21945129 | 0.83 | KCNH2 (0.37) | CYP19A1HDAC1 | |
| SCHEMBL10155081 | 0.83 | RAF1 (0.33) | L3MBTL1 | |
| SCHEMBL294779 | 0.82 | HDAC1 (0.35) | HDAC1KDM5AKDM4CKDM5B | |
| SCHEMBL15884803 | 0.82 | CYP4F2 (0.40) | CYP19A1HDAC1KDM5AKDM4CKDM5B | |
| SCHEMBL12844612 | 0.80 | CYP19A1 (0.46) | CYP19A1HDAC1 | |
| SCHEMBL293599 | 0.80 | HDAC1 (0.36) | HDAC1KDM5AKDM4CKDM5B | |
| SCHEMBL442894 | 0.80 | PRMT5 (0.30) | L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103732589-B | Can be used as the sulphonamide of the replacement of anti-apoptotic BCL inhibitor | BRISTOL-MYERS SQUIBB CO. (US) | 2016-03-30 | — | — | CN | disclosed |