Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28077602 | 0.82 | — | — | |
| SCHEMBL28106912 | 0.82 | KDM4E (0.33) | — | |
| SCHEMBL28025793 | 0.77 | — | — | |
| SCHEMBL28290792 | 0.74 | CYP2D6 (0.31) | — | |
| SCHEMBL28821594 | 0.73 | ELANE (0.38) | ELANE | |
| SCHEMBL27830203 | 0.73 | KDM4E (0.32) | — | |
| SCHEMBL27947173 | 0.72 | ELANE (0.32) | ELANE | |
| SCHEMBL321953 | 0.67 | — | — | |
| SCHEMBL28026347 | 0.67 | — | — | |
| SCHEMBL22414460 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105408328-A | sGC stimulators | IRONWOOD PHARMACEUTICALS INC | 2016-03-16 | — | — | CN | disclosed |