SCHEMBL28106912

SCHEMBL28106912

CC(C)(C)C(=O)OC1(CN)CCNCC1

nearest known ligand 0.38

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.33
KMT2A Q03164 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28077602 0.87
SCHEMBL27830203 0.87 KDM4E (0.32) KDM4EKMT2A
SCHEMBL28056934 0.82 ELANE (0.30)
SCHEMBL28023211 0.79 OPRM1 (0.33)
SCHEMBL27830224 0.79 OPRM1 (0.30)
SCHEMBL28023823 0.79 KDM4E (0.31) KDM4EKMT2A
SCHEMBL28023233 0.79 CYP4F2 (0.32)
SCHEMBL28290792 0.78 CYP2D6 (0.31)
SCHEMBL28835285 0.78 KDM4E (0.30) KDM4EKMT2A
SCHEMBL27857663 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106103445-B The therapeutical uses of pyrazolo [1,5-A] pyrimidine -5,7- diamine compound and they as CDK inhibitor 癌症研究技术有限公司 2019-08-09 CN disclosed
CN-110088096-A Piperidine derivatives as inhibitors of ubiquitin-specific protease 7 阿尔麦克探索有限公司 2019-08-02 CN disclosed
CN-104350055-B Bicyclic heteroaryl derivatives and application thereof as MNK1 and MNK2 regulator 新加坡科技研究局 2019-05-31 CN disclosed
CN-106103445-A Pyrazolo [1,5 A] pyrimidine 5,7 diamine compound and their therapeutic use as CDK inhibitor 癌症研究技术有限公司 2016-11-09 CN disclosed
CN-104350055-A Bicyclic heterocyclic derivatives as MNK1 and MNK2 modulators and uses thereof AGENCY SCIENCE TECH & RES (SG) 2015-02-11 CN disclosed
CN-101522668-B Oxyindole derivatives as 5ht4 receptor agonists PFIZER 2012-06-06 CN disclosed
CN-102083839-A Compound (I) ASTRAZENECA AB 2011-06-01 CN disclosed
CN-101522668-A Oxyindole derivatives as 5ht4 receptor agonists PFIZER JAPAN INC (US) 2009-09-02 CN disclosed