Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN4A | P35499 | 7/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 2/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27007450 | 0.85 | SCN4A (0.55) | SCN4AKMT2ANPC1RAB9ACA1 | |
| SCHEMBL27774356 | 0.83 | CYP19A1 (0.54) | SCN4AKMT2ANPC1RAB9ACA1 | |
| SCHEMBL29095292 | 0.83 | SCN4A (0.52) | SCN4AKMT2ANPC1RAB9ACA1 | |
| SCHEMBL29095278 | 0.82 | SCN4A (0.48) | SCN4AKMT2ANPC1RAB9ACA1 | |
| SCHEMBL27568216 | 0.75 | SCN4A (0.47) | SCN4AKMT2ACA1CA2LTA4H | |
| SCHEMBL15563236 | 0.74 | SCN4A (0.49) | SCN4AKMT2ANPC1RAB9ACA1 | |
| SCHEMBL27568071 | 0.73 | SCN4A (0.61) | SCN4AKMT2ANPC1RAB9ACA1 | |
| SCHEMBL27568214 | 0.72 | SCN4A (0.44) | SCN4AKMT2ALTA4H | |
| SCHEMBL17206355 | 0.72 | KMT2A (0.53) | SCN4AKMT2ANPC1RAB9ACYP19A1 | |
| SCHEMBL27774531 | 0.71 | LTA4H (0.41) | SCN4AKMT2ACYP19A1LTA4HKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105451741-A | Inhibitors of bruton's tyrosine kinase | FUJIAN HAIXI PHARMACEUTICALS CO LTD | 2016-03-30 | — | — | CN | disclosed |