Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTAFR | P25105 | 1/20 | 0.30 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.30 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28057297 | 0.98 | PTAFR (0.31) | PTAFRTRIM24TRIM33 | |
| SCHEMBL12671542 | 0.74 | CHRM2 (0.35) | — | |
| SCHEMBL7945184 | 0.72 | KDM4E (0.33) | — | |
| SCHEMBL990793 | 0.72 | HDAC3 (0.38) | — | |
| SCHEMBL21465809 | 0.71 | PARP1 (0.36) | — | |
| Hydrochloric Acid SCHEMBL28318712 | 0.70 | HDAC3 (0.38) | — | |
| SCHEMBL23666018 | 0.70 | LMNA (0.32) | — | |
| SCHEMBL27678947 | 0.67 | CRBN (0.30) | — | |
| SCHEMBL28319875 | 0.67 | PDE3B (0.34) | — | |
| SCHEMBL13859949 | 0.65 | TSHR (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105358551-A | Octahydro-cyclopentapyrrolyl antagonists of CCR2 | JANSSEN PHARMACEUTICA NV | 2016-02-24 | — | — | CN | disclosed |