SCHEMBL28057877

SCHEMBL28057877

CCCCC(C=O)(C=O)OC

nearest known ligand 0.35

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.35
FDPS P14324 1/20 0.31
ADH1B P00325 2/20 0.31
ADH1C P00326 2/20 0.31
ADH1A P07327 2/20 0.31
ADH7 P40394 2/20 0.31
EPHX1 P07099 1/20 0.30
ADH4 P08319 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8624273 0.76 ADH1B (0.36) TSHRFDPSADH1BADH1CADH1A
SCHEMBL8743504 0.74 TSHR (0.33) TSHRFDPSADH1BADH1CADH1A
SCHEMBL28115109 0.73 TSHR (0.32) TSHR
SCHEMBL8923107 0.70 ADH1B (0.38) TSHRFDPSADH1BADH1CADH1A
SCHEMBL8924793 0.68 EPHX1 (0.41) TSHRFDPSADH1BADH1CADH1A
SCHEMBL8924684 0.68 EPHX1 (0.41) TSHRFDPSADH1BADH1CADH1A
SCHEMBL9774445 0.68 EPHX1 (0.41) TSHRFDPSADH1BADH1CADH1A
SCHEMBL5528700 0.68 EPHX1 (0.41) TSHRFDPSADH1BADH1CADH1A
SCHEMBL8921966 0.68 EPHX1 (0.41) TSHRFDPSADH1BADH1CADH1A
SCHEMBL21276960 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103261140-B Process for producing dibenzoylmethane derivative DSM IP ASSETS B.V. (NL) 2016-04-06 CN disclosed