Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Diethylamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | SAT1 | P21673 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Diethylamine SCHEMBL2588947 | 0.85 | — | — | |
| Diethylamine SCHEMBL3257941 | 0.85 | — | — | |
| Diethylamine SCHEMBL28353038 | 0.82 | TP53 (0.57) | TP53MCL1 | |
| Propyne SCHEMBL30915801 | 0.82 | — | — | |
| Diethylamine SCHEMBL29021919 | 0.81 | TP53 (0.42) | TP53MCL1 | |
| Diethylamine SCHEMBL27350955 | 0.74 | TP53 (0.47) | TP53 | |
| Diethylamine SCHEMBL27899654 | 0.71 | — | — | |
| Diethylamine SCHEMBL27836291 | 0.71 | — | — | |
| Hexane SCHEMBL28985133 | 0.70 | TSHR (0.43) | TP53 | |
| Formic Acid SCHEMBL5387621 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105648480-A | Full-bright nickel plating major brightening agent and preparing method thereof | 湖北德美科技有限公司 | 2016-06-08 | — | — | CN | disclosed |
| CN-105463519-A | Barrel nickel plating major brightening agent and preparation method thereof | HUBEI DE MEI TECH CO LTD | 2016-04-06 | — | — | CN | disclosed |