Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Diethylamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 5/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ADH1B | P00325 | 1/20 | 0.32 |
| ▸ | ADH1A | P07327 | 1/20 | 0.32 |
| ▸ | ADH7 | P40394 | 1/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Diethylamine SCHEMBL2588947 | 0.96 | — | — | |
| Diethylamine SCHEMBL29021919 | 0.86 | TP53 (0.42) | TP53MCL1 | |
| Diethylamine SCHEMBL509438 | 0.84 | — | — | |
| Diethylamine SCHEMBL27350955 | 0.84 | TP53 (0.47) | TP53ALDH1A1MAPK1TDP1CYP2C19 | |
| Diethylamine SCHEMBL28058192 | 0.82 | TP53 (0.44) | TP53MCL1 | |
| Diethylamine SCHEMBL11583123 | 0.81 | TP53 (0.73) | TP53ALDH1A1CYP2C19MEN1GLA | |
| Diethylamine SCHEMBL11565851 | 0.81 | TP53 (0.73) | TP53ALDH1A1CYP2C19MEN1GLA | |
| Diethylamine SCHEMBL4046893 | 0.81 | — | — | |
| Diethylamine SCHEMBL27836291 | 0.81 | — | — | |
| Diethylamine SCHEMBL27879298 | 0.81 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117686611-A | Detection method for determining oxaagole sodium isomer by HPLC | 哈药集团技术中心 | 2024-03-12 | — | — | CN | claimed |
| CN-117686611-A | Detection method for determining oxaagole sodium isomer by HPLC | 哈药集团技术中心 | 2024-03-12 | — | — | CN | disclosed |
| CN-110596294-B | High performance liquid detection method of glycyl-D-glutamine | 山东威高药业股份有限公司 | 2021-07-06 | — | — | CN | disclosed |
| CN-110596294-A | High performance liquid detection method of glycyl-D-glutamine | 山东威高药业股份有限公司 | 2019-12-20 | — | — | CN | disclosed |