Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1902979 | 0.75 | APOBEC3G (0.52) | HSD11B1SMN1; SMN2LMNATSHRAPOBEC3G | |
| SCHEMBL29095317 | 0.72 | APOBEC3G (0.48) | HSD11B1LMNAAPOBEC3GALDH1A1KMT2A | |
| SCHEMBL3018655 | 0.72 | F2 (0.52) | HSD11B1MAPTSMN1; SMN2F2LMNA | |
| SCHEMBL3026702 | 0.71 | F2 (0.50) | HSD11B1MAPTSMN1; SMN2F2LMNA | |
| SCHEMBL5974785 | 0.71 | F2 (0.50) | HSD11B1MAPTSMN1; SMN2F2LMNA | |
| SCHEMBL17225124 | 0.70 | MEN1 (0.52) | MAPTSMN1; SMN2KMT2AL3MBTL1POLB | |
| SCHEMBL30817520 | 0.70 | APOBEC3G (0.50) | HSD11B1SMN1; SMN2TSHRAPOBEC3GALDH1A1 | |
| SCHEMBL3018658 | 0.69 | F2 (0.59) | HSD11B1MAPTSMN1; SMN2F2LMNA | |
| SCHEMBL3026705 | 0.69 | F2 (0.59) | HSD11B1MAPTSMN1; SMN2F2LMNA | |
| SCHEMBL28696634 | 0.69 | APOBEC3G (0.54) | HSD11B1SMN1; SMN2TSHRAPOBEC3GALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102161743-B | Solvent-free aqueous polyurethane dispersion and preparation and application thereof | AIR PRODUCTS AND CHEMICALS, INC. (US) | 2016-04-06 | — | — | CN | disclosed |