Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | TAS2R14 | Q9NYV8 | 2/20 | 0.49 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.49 |
| ▸ | FLT1 | P17948 | 1/20 | 0.47 |
| ▸ | FLT4 | P35916 | 1/20 | 0.47 |
| ▸ | KDR | P35968 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.44 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA3 | P07451 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18488891 | 0.83 | MEN1 (0.48) | MEN1KMT2AALOX15TP53TAS2R14 | |
| SCHEMBL1643247 | 0.80 | MEN1 (0.79) | MEN1KMT2AALOX15TP53TAS2R14 | |
| SCHEMBL1950189 | 0.73 | ITGAV (0.40) | KMT2AL3MBTL1MAPTSMN1; SMN2 | |
| SCHEMBL11603992 | 0.71 | TP53 (0.55) | MEN1KMT2ATP53TAS2R14CXCR3 | |
| SCHEMBL28058202 | 0.70 | HSD11B1 (0.49) | KMT2AL3MBTL1MAPTPOLBSMN1; SMN2 | |
| SCHEMBL31495844 | 0.70 | TP53 (0.50) | MEN1KMT2ATP53TAS2R14CXCR3 | |
| SCHEMBL1169742 | 0.70 | TP53 (0.79) | MEN1KMT2ATP53TAS2R14CXCR3 | |
| SCHEMBL1947890 | 0.69 | MEN1 (1.00) | MEN1KMT2AALOX15TP53MAPT | |
| SCHEMBL11448337 | 0.69 | HSD11B1 (0.51) | MEN1KMT2ATP53TAS2R14CXCR3 | |
| Benzoyl Peroxide SCHEMBL10536706 | 0.68 | LMNA (0.74) | MEN1KMT2AALOX15TP53L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3137068-A1 | TREATMENT OF FIBROSIS | UCL Business Plc. (GB) | 2017-03-08 | — | — | EP | disclosed |
| WO-2015166277-A1 | TREATMENT OF FIBROSIS | UCL BUSINESS PLC (GB) | 2015-11-05 | — | — | WO | disclosed |