Acrylamide

Acrylamide

SCHEMBL28058271

C=CC(N)=O.C=CC(N)=O.C=CCC(=O)OCCC

nearest known ligand 0.41

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Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.41
TSHR P16473 4/20 0.41
FGFR4 P22455 1/20 0.41
HPGD P15428 1/20 0.40
HTT P42858 1/20 0.39
HCAR2 Q8TDS4 1/20 0.36
MAPK1 P28482 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
NAAA Q02083 1/20 0.33
DGKA P23743 1/20 0.33
GAA P10253 1/20 0.33
PPM1B O75688 1/20 0.33
PTPN1 P18031 1/20 0.33
PPP1CC P36873 1/20 0.33
CYP3A4 P08684 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2985169 0.90
Acrylamide SCHEMBL27572677 0.85 NAAA (0.48) ALDH1A1TSHRFGFR4HPGDHTT
Acrylamide SCHEMBL28142514 0.85 NAAA (0.48) ALDH1A1TSHRFGFR4HPGDHTT
Maleic Acid SCHEMBL28703536 0.81 HCAR2 (0.58) ALDH1A1TSHRHPGDHTTHCAR2
SCHEMBL164111 0.79 TSHR (0.59) ALDH1A1TSHRHPGDHTTHCAR2
Acrylamide SCHEMBL27812978 0.79 TSHR (0.64) ALDH1A1TSHRFGFR4HPGDHCAR2
SCHEMBL33704 0.77 HTT (0.49) ALDH1A1TSHRHPGDHTTDGKA
SCHEMBL793169 0.77 NAAA (0.59) ALDH1A1TSHRHPGDHTTHCAR2
Acrylamide SCHEMBL7790400 0.76 TSHR (0.48) ALDH1A1TSHRFGFR4MAPK1GAA
Acrylamide SCHEMBL22499613 0.76 TSHR (0.52) ALDH1A1TSHRFGFR4HPGDHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105330786-B Ultrasonic coupling medium material for treatment and preparation method thereof 重庆海扶医疗科技股份有限公司 2017-07-14 CN disclosed
CN-105330786-A Ultrasonic coupling medium material for treatment and preparation method thereof CHONGQING HAIFU MEDICAL TECHNOLOGY CO LTD 2016-02-17 CN disclosed