Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 11/20 | 0.47 |
| ▸ | OPRD1 | P41143 | 11/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 11/20 | 0.47 |
| ▸ | OPRL1 | P41146 | 11/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.39 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7470789 | 0.98 | OPRM1 (0.48) | OPRM1OPRD1OPRK1OPRL1EPHX2 | |
| SCHEMBL16954110 | 0.95 | OPRM1 (0.49) | OPRM1OPRD1OPRK1OPRL1AOC3 | |
| SCHEMBL16956482 | 0.87 | OPRM1 (0.44) | OPRM1OPRD1OPRK1OPRL1AOC3 | |
| SCHEMBL23344676 | 0.83 | OPRM1 (0.49) | OPRM1OPRD1OPRK1OPRL1EPHX2 | |
| SCHEMBL22571302 | 0.83 | OPRM1 (0.49) | OPRM1OPRD1OPRK1OPRL1EPHX2 | |
| SCHEMBL20091088 | 0.83 | OPRM1 (0.47) | OPRM1OPRD1OPRK1OPRL1EPHX2 | |
| SCHEMBL26381712 | 0.81 | OPRM1 (0.46) | OPRM1OPRD1OPRK1OPRL1EPHX2 | |
| SCHEMBL19523042 | 0.81 | OPRM1 (0.48) | OPRM1OPRD1OPRK1OPRL1EPHX2 | |
| SCHEMBL18885428 | 0.80 | OPRM1 (0.47) | OPRM1OPRD1OPRK1OPRL1EPHX2 | |
| SCHEMBL3086005 | 0.80 | AOC3 (0.44) | OPRM1OPRD1OPRK1OPRL1AOC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105358534-A | Novel synthetic process to 8-chloro-1-methyl-benzo[d]azepine, novel intermediates and the production thereof | LEK PHARMACEUTICALS | 2016-02-24 | — | — | CN | disclosed |