Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 5/20 | 0.52 |
| ▸ | NPC1 | O15118 | 4/20 | 0.52 |
| ▸ | TP53 | P04637 | 3/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | KDM1A | O60341 | 2/20 | 0.47 |
| ▸ | MAOA | P21397 | 2/20 | 0.47 |
| ▸ | MAOB | P27338 | 2/20 | 0.47 |
| ▸ | KDM1B | Q8NB78 | 2/20 | 0.47 |
| ▸ | RCOR1 | Q9UKL0 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28059187 | 0.90 | MAPT (0.68) | MAPTHDAC8HDAC6RAB9ANPC1 | |
| SCHEMBL28059240 | 0.84 | MAPT (0.57) | MAPTHDAC8HDAC6RAB9ANPC1 | |
| SCHEMBL28059320 | 0.84 | MAPT (0.53) | MAPTHDAC8HDAC6RAB9ANPC1 | |
| SCHEMBL1663615 | 0.84 | MAPT (0.70) | MAPTHDAC8HDAC6RAB9ANPC1 | |
| SCHEMBL28059225 | 0.83 | RAB9A (0.57) | MAPTHDAC8HDAC6RAB9ANPC1 | |
| SCHEMBL28059163 | 0.83 | MAPT (0.55) | MAPTHDAC8HDAC6RAB9ANPC1 | |
| SCHEMBL28059289 | 0.83 | MAPT (0.54) | MAPTHDAC8HDAC6RAB9ANPC1 | |
| SCHEMBL27868346 | 0.82 | HDAC8 (0.54) | MAPTHDAC8HDAC6RAB9ANPC1 | |
| SCHEMBL28826938 | 0.80 | HDAC8 (0.52) | MAPTHDAC8HDAC6RAB9ANPC1 | |
| SCHEMBL28059242 | 0.80 | HDAC8 (0.54) | MAPTHDAC8HDAC6RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102656141-B | Micromolecular compound of simulation hemopoieticgrowth factor and uses thereof | LIGAND PHARMACEUTICALS INC. (US) | 2016-04-06 | — | — | CN | disclosed |