Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 11/20 | 0.56 |
| ▸ | RAB9A | P51151 | 11/20 | 0.56 |
| ▸ | NPC1 | O15118 | 9/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | TP53 | P04637 | 3/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1662875 | 0.85 | MAPT (0.70) | MAPTRAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL8773851 | 0.84 | MAPT (0.64) | MAPTRAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL27884842 | 0.83 | HDAC8 (0.53) | MAPTRAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL27868424 | 0.82 | RAB9A (0.71) | MAPTRAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL1663970 | 0.79 | MAPT (0.56) | MAPTRAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL1663971 | 0.78 | MAPT (0.61) | MAPTRAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL1663783 | 0.78 | HDAC8 (0.81) | MAPTRAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL28059187 | 0.77 | MAPT (0.68) | MAPTRAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL27868346 | 0.77 | HDAC8 (0.54) | MAPTRAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL13964718 | 0.76 | MAPT (0.67) | MAPTRAB9ANPC1SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102656141-B | Micromolecular compound of simulation hemopoieticgrowth factor and uses thereof | LIGAND PHARMACEUTICALS INC. (US) | 2016-04-06 | — | — | CN | disclosed |