SCHEMBL28059294

SCHEMBL28059294

C[Si](C)(C)OS(C)(=O)=O.FC(F)F

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.33
USP2 O75604 1/20 0.33
TSHR P16473 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL537775 0.88
SCHEMBL9898501 0.80 CA2 (0.35) USP2TSHR
SCHEMBL20537334 0.76 CA2 (0.38) TSHR
Ether SCHEMBL5998261 0.74 USP2 (0.30) USP2TSHR
SCHEMBL1516355 0.72
SCHEMBL14779541 0.69 USP2 (0.41) ALDH1A1USP2TSHR
Methanesulfonic Acid Methyl Ester SCHEMBL28836072 0.69 USP2 (0.71) ALDH1A1USP2TSHR
SCHEMBL1059932 0.69
SCHEMBL1903798 0.67
SCHEMBL7715534 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105492075-B Inhibitors of viral replication, their preparation method and their therapeutical uses HIVIH公司 2019-11-12 CN disclosed
CN-105492075-A Inhibitors of viral replication, their process of preparation and their therapeutical uses MUTABILIS SA 2016-04-13 CN disclosed