Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 7/20 | 0.47 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.45 |
| ▸ | PLAU | P00749 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | S100A4 | P26447 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5780887 | 0.86 | TDP1 (0.56) | SMN1; SMN2TDP1GPR35PLAUTSHR | |
| SCHEMBL2413571 | 0.83 | SMN1; SMN2 (0.46) | SMN1; SMN2PDE7ATDP1GPR35PLAU | |
| SCHEMBL3345170 | 0.78 | TDP1 (0.48) | SMN1; SMN2TDP1GPR35PLAUTSHR | |
| SCHEMBL28175713 | 0.77 | TSHR (0.60) | SMN1; SMN2TDP1GPR35PLAUTSHR | |
| SCHEMBL29448254 | 0.75 | TDP1 (0.60) | SMN1; SMN2PDE7ATDP1GPR35TSHR | |
| SCHEMBL24548 | 0.75 | TDP1 (0.60) | SMN1; SMN2PDE7ATDP1GPR35TSHR | |
| 2-Nitroaniline SCHEMBL29396517 | 0.74 | PDE7A (0.62) | SMN1; SMN2PDE7ATDP1GPR35PLAU | |
| SCHEMBL10381945 | 0.74 | PDE7A (0.62) | SMN1; SMN2PDE7ATDP1GPR35PLAU | |
| 2-Nitroaniline SCHEMBL6000 | 0.74 | PDE7A (0.62) | SMN1; SMN2PDE7ATDP1GPR35PLAU | |
| SCHEMBL17934 | 0.74 | TSHR (0.59) | SMN1; SMN2PDE7ATDP1GPR35TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105377831-A | Synthesis of 3- (5-amino-2-methyl-4-oxoquinazolin-3 (4H) -yl) piperidine-2, 6-dione | CELGENE CORP | 2016-03-02 | — | — | CN | disclosed |