2-Nitroaniline

2-Nitroaniline

SCHEMBL6000

Nc1ccccc1[N+](=O)[O-]

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
PDE7A Q13946 2/20 0.62
SMN1; SMN2 Q16637 1/20 0.62
TDP1 Q9NUW8 7/20 0.56
ALDH1A1 P00352 5/20 0.56
TSHR P16473 3/20 0.56
MEN1 O00255 2/20 0.56
KMT2A Q03164 2/20 0.56
POLB P06746 1/20 0.56
MAPT P10636 1/20 0.56
CYP3A4 P08684 1/20 0.56
ALOX15 P16050 1/20 0.56
HSD17B10 Q99714 1/20 0.54
GPR35 Q9HC97 1/20 0.50
MAPK1 P28482 1/20 0.50
PLAU P00749 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
2-Nitroaniline SCHEMBL29396517 1.00 PDE7A (0.62) PDE7ASMN1; SMN2TDP1ALDH1A1TSHR
2-Nitroaniline SCHEMBL3094201 0.98 PDE7A (0.60) PDE7ASMN1; SMN2TDP1ALDH1A1TSHR
2-Nitroaniline SCHEMBL20876419 0.98 PDE7A (0.60) PDE7ASMN1; SMN2TDP1ALDH1A1TSHR
2-Nitroaniline SCHEMBL28878330 0.98 PDE7A (0.60) PDE7ASMN1; SMN2TDP1ALDH1A1TSHR
2-Nitroaniline SCHEMBL859788 0.98 PDE7A (0.60) PDE7ASMN1; SMN2TDP1ALDH1A1TSHR
2-Nitroaniline SCHEMBL5718349 0.98 PDE7A (0.60) PDE7ASMN1; SMN2TDP1ALDH1A1TSHR
2-Nitroaniline SCHEMBL5331149 0.98 PDE7A (0.60) PDE7ASMN1; SMN2TDP1ALDH1A1TSHR
2-Nitroaniline SCHEMBL859790 0.98 PDE7A (0.60) PDE7ASMN1; SMN2TDP1ALDH1A1TSHR
2-Nitroaniline SCHEMBL355101 0.98 PDE7A (0.60) PDE7ASMN1; SMN2TDP1ALDH1A1TSHR
2-Nitroaniline SCHEMBL28069602 0.98 PDE7A (0.60) PDE7ASMN1; SMN2TDP1ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 18990 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117965919-B Preparation method and application of carbon-supported platinum group metal-based high-entropy alloy Changzhou University (CN) 2026-05-26 CN claimed
WO-2026107261-A1 PURIFICATION OF PHOTORESIST POLYMER BY SURFACE-MODIFIED POROUS POLYETHYLENE MEMBRANE ENTEGRIS, INC. (US) 2026-05-21 WO claimed
CN-122070354-A Shear stable aluminum complex grease 路博润公司 2026-05-19 CN claimed
CN-115679430-B Titanium-aluminum composite part film removing treatment agent and titanium-aluminum composite part surface micropore treatment method 东莞市慧泽凌化工科技有限公司 2026-05-19 CN claimed
CN-122055148-A Conjugates, compositions and methods for treating influenza 珀杜研究基金会 2026-05-15 CN claimed
CN-121108414-B Raw material composition for preparing medium-high refractive index polyurethane optical material 江苏视科新材料股份有限公司 2026-05-12 CN claimed
US-12624144-B2 Method for preparing hollow covalent organic framework materials ZHEJIANG UNIVERSITY (CN) 2026-05-12 US claimed
CN-122010953-A Pyrazolo [1, 5-alpha ] pyrimidine compound, and synthetic method and application thereof 豫北医学院 2026-05-12 CN claimed
US-20260110656-A1 ELECTROCHEMICAL SENSOR PREPARED FROM NIOBIUM CARBIDE-REDUCED GRAPHENE OXIDE AEROGEL COMPOSITE MATERIAL AND ITS UTILIZATION NATIONAL TAIPEI UNIVERSITY OF TECHNOLOGY (TW) 2026-04-23 US claimed
EP-3338813-B2 MULTI-LAYER WOUND CARE PRODUCT WITH PERFORATED RELEASE LAYER BSN MEDICAL GMBH (DE) 2026-04-15 EP claimed
US-4048006-A Stripping of electroplated nickel-iron alloys M&T CHEMICALS INC. (US) 1977-09-13 US claimed
US-4042451-A Selected stripping of nickel-iron alloys from ferrous substrates M&T CHEMICALS INC. (US) 1977-08-16 US claimed
US-4036680-A Delignification of lignocellulosic material with a soda pulping liquor containing a Diels Alder adduct of benzoquinone or naphthoquinone in admixture with a nitro aromatic compound CANADIAN INDUSTRIES, LTD. (CA) 1977-07-19 US claimed
US-4021382-A Method for the preparation of hydrophilic spongy gels CESKOSLOVENSKA AKADEMIE VED (CS) 1977-05-03 US claimed
US-4007221-A Manufacture of nuclear-iodinated iodine compounds of aromatic character BASF AKTIENGESELLSCHAFT (DT) 1977-02-08 US claimed
US-3972878-A Method for preparing azines and hydrazones PRODUITS CHIMIQUES UGINE KUHLMANN (FR) 1976-08-03 US claimed
US-3966817-A Herbicidal ortho-nitroanilines SHELL OIL COMPANY (US) 1976-06-29 US claimed
US-3961884-A Process for dyeing textile material of polyester fiber/cellulose blends HOECHST AKTIENGESELLSCHAFT (DT) 1976-06-08 US claimed
US-3948667-A HOMO- AND CO-POLYMERS OF CYCLIZED BUTADIENE AND A CROSSLINKING AGENT JAPAN SYNTHETIC RUBBER COMPANY LIMITED (JA) 1976-04-06 US claimed
US-3936429-A Reactive polymer FUJI PHOTO FILM CO., LTD. (JA) 1976-02-03 US claimed