Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 3/20 | 0.41 |
| ▸ | CA9 | Q16790 | 3/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA3 | P07451 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1463596 | 0.83 | KMT2A (0.48) | KMT2AGAAALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL28217312 | 0.82 | ALDH1A1 (0.47) | KMT2AGAAALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL8410970 | 0.80 | CYP1A2 (0.47) | KMT2AGAAALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL25936836 | 0.78 | CYP4F2 (0.50) | KMT2AGAAALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL9850245 | 0.77 | POLB (0.44) | KMT2AGAAALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL15457438 | 0.75 | CYP4F2 (0.50) | KMT2AGAAALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL20925382 | 0.74 | KMT2A (0.46) | KMT2AGAAALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL4810364 | 0.74 | ALDH1A1 (0.51) | KMT2AGAAALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL8473010 | 0.74 | ALDH1A1 (0.49) | KMT2AGAAALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL17662446 | 0.74 | ALDH1A1 (0.46) | KMT2AGAAALDH1A1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105481748-B | Polysubstituted dihydro pyrrole derivates of 5- fluorine and preparation method thereof | 华东师范大学 | 2018-05-15 | — | — | CN | disclosed |
| CN-105481748-A | 5-fluoro polysubstituted pyrroline derivative and preparation method thereof | UNIV EAST CHINA NORMAL | 2016-04-13 | — | — | CN | disclosed |