Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.40 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.40 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.38 |
| ▸ | USP19 | O94966 | 1/20 | 0.38 |
| ▸ | TNFSF11 | O14788 | 1/20 | 0.38 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.37 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | TACR1 | P25103 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1278327 | 0.93 | NAMPT (0.39) | NAMPTCHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL1156525 | 0.91 | POLB (0.42) | NAMPTCHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL1156410 | 0.91 | PTGDR2 (0.42) | NAMPTCHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL3914395 | 0.91 | NAMPT (0.39) | NAMPTCHRNB2CHRNB4CHRNA3CHRNA4 | |
| Fumaric Acid SCHEMBL31647335 | 0.90 | CHRNB2 (0.39) | NAMPTCHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL1560973 | 0.90 | NAMPT (0.39) | NAMPTLMNAALDH1A1PTGDR2GPBAR1 | |
| SCHEMBL1156671 | 0.90 | TACR1 (0.43) | NAMPTLMNAALDH1A1KDM4ETACR1 | |
| SCHEMBL30620797 | 0.89 | CHRNB2 (0.39) | NAMPTCHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL30620799 | 0.89 | CHRNB2 (0.39) | NAMPTCHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL28631600 | 0.89 | CHRNB2 (0.39) | NAMPTCHRNB2CHRNB4CHRNA3CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105461690-A | Preparation method of high-purity tert-butyl ((5-(2-fluorophenyl)-1-(pyridine-3-yl sulfonyl)-1H-pyrrole-3-yl)methyl)(methyl)carbamate | NANJING JIQUN PHARMACEUTICAL SCIENCE AND TECH CO LTD | 2016-04-06 | — | — | CN | disclosed |
| CN-105461690-A | Preparation method of high-purity tert-butyl ((5-(2-fluorophenyl)-1-(pyridine-3-yl sulfonyl)-1H-pyrrole-3-yl)methyl)(methyl)carbamate | NANJING JIQUN PHARMACEUTICAL SCIENCE AND TECH CO LTD | 2016-04-06 | — | — | CN | disclosed |