SCHEMBL28059944

SCHEMBL28059944

CNCCCN(CN)CN

nearest known ligand 0.39

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.39
PRMT3 O60678 1/20 0.38
CARM1 Q86X55 1/20 0.38
PRMT6 Q96LA8 1/20 0.38
PRMT1 Q99873 1/20 0.38
PRMT8 Q9NR22 1/20 0.38
EPHX1 P07099 1/20 0.36
CYP2C9 P11712 1/20 0.32
CYP2C19 P33261 1/20 0.32
HTR2A P28223 1/20 0.31
HRH1 P35367 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15569827 0.83 PRMT3 (0.45) PRMT3CARM1PRMT6PRMT1PRMT8
SCHEMBL28251166 0.82 TDP1 (0.43) TDP1PRMT3CARM1PRMT6PRMT1
SCHEMBL8306309 0.82 LCK (0.41) TDP1PRMT3CARM1PRMT6PRMT1
SCHEMBL10903010 0.82 TDP1 (0.43) TDP1PRMT3CARM1PRMT6PRMT1
SCHEMBL24719523 0.78 LCK (0.39) TDP1PRMT3CARM1PRMT6PRMT1
SCHEMBL13867483 0.78 EPHX1 (0.46) PRMT3CARM1PRMT6PRMT1PRMT8
Hydrochloric Acid SCHEMBL8850841 0.77 CHRM2 (0.44) TDP1EPHX1
SCHEMBL26207 0.76 PAOX (0.44) PRMT3CARM1PRMT6PRMT1PRMT8
SCHEMBL18912766 0.76 EPHX1 (0.43) PRMT3CARM1PRMT6PRMT1PRMT8
SCHEMBL19607935 0.75 CHRM2 (0.42) TDP1PRMT3CARM1PRMT6PRMT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104250357-B A kind of acrylamide based copolymer and its preparation method and application SINOPEC CORP. (CN) 2016-05-25 CN disclosed