Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Gallic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 4/20 | 0.90 |
| ▸ | CA1 | P00915 | 4/20 | 0.90 |
| ▸ | CA2 | P00918 | 4/20 | 0.90 |
| ▸ | CA7 | P43166 | 4/20 | 0.90 |
| ▸ | CA9 | Q16790 | 4/20 | 0.90 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.90 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.90 |
| ▸ | MAPT | P10636 | 3/20 | 0.90 |
| ▸ | CA4 | P22748 | 3/20 | 0.90 |
| ▸ | CA6 | P23280 | 3/20 | 0.90 |
| ▸ | LMNA | P02545 | 3/20 | 0.90 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.90 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.90 |
| ▸ | FUT7 | Q11130 | 2/20 | 0.90 |
| ▸ | CA3 | P07451 | 2/20 | 0.90 |
| ▸ | CA5A | P35218 | 2/20 | 0.90 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.90 |
| ▸ | TP53 | P04637 | 1/20 | 0.90 |
| ▸ | SELL | P14151 | 1/20 | 0.90 |
| ▸ | HPGD | P15428 | 1/20 | 0.90 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Gallic Acid SCHEMBL29282650 | 0.95 | CA12 (0.90) | CA12CA1CA2CA7CA9 | |
| Gallic Acid SCHEMBL29484566 | 0.95 | CA12 (1.00) | CA12CA1CA2CA7CA9 | |
| Gallic Acid SCHEMBL15012 | 0.95 | CA12 (1.00) | CA12CA1CA2CA7CA9 | |
| Gallic Acid SCHEMBL4918056 | 0.95 | CA12 (1.00) | CA12CA1CA2CA7CA9 | |
| Gallic Acid SCHEMBL678990 | 0.95 | CA12 (1.00) | CA12CA1CA2CA7CA9 | |
| Gallic Acid SCHEMBL30375631 | 0.95 | CA12 (1.00) | CA12CA1CA2CA7CA9 | |
| Gallic Acid SCHEMBL8088102 | 0.95 | CA12 (1.00) | CA12CA1CA2CA7CA9 | |
| Gallic Acid SCHEMBL1845406 | 0.95 | CA12 (1.00) | CA12CA1CA2CA7CA9 | |
| Gallic Acid SCHEMBL1738964 | 0.92 | CA12 (0.94) | CA12CA1CA2CA7CA9 | |
| Gallic Acid SCHEMBL17964346 | 0.92 | CA12 (0.94) | CA12CA1CA2CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105482003-A | Carrier for ethylene polymerization catalyst and catalyst of carrier | CHINA PETROLEUM & CHEM CORP | 2016-04-13 | — | — | CN | disclosed |