SCHEMBL28060015

SCHEMBL28060015

CCCn1ccnc1-c1ccccn1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 6/20 0.44
SMN1; SMN2 Q16637 5/20 0.44
TP53 P04637 4/20 0.44
TSHR P16473 1/20 0.44
KDM4E B2RXH2 5/20 0.43
LMNA P02545 3/20 0.43
POLB P06746 2/20 0.43
CYP1A2 P05177 2/20 0.43
CCR1 P32246 2/20 0.43
CCR5 P51681 2/20 0.43
CCR8 P51685 2/20 0.43
METAP1 P53582 1/20 0.43
BLM P54132 1/20 0.43
HIF1A Q16665 1/20 0.43
DOHH Q9BU89 1/20 0.43
P4HTM Q9NXG6 1/20 0.43
ALDH1A1 P00352 3/20 0.43
KMT2A Q03164 1/20 0.43
ESR1 P03372 1/20 0.43
CYP2D6 P10635 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27908771 0.90 POLB (0.57) NPC1SMN1; SMN2TP53TSHRKDM4E
SCHEMBL5612943 0.89 TLR8 (0.53) NPC1SMN1; SMN2TP53TSHRKDM4E
SCHEMBL11226113 0.87 TLR8 (0.51) POLBCYP1A2BLMALDH1A1KMT2A
SCHEMBL16502267 0.87 TLR8 (0.51) POLBCYP1A2BLMALDH1A1KMT2A
SCHEMBL6357965 0.86 TP53 (0.47) NPC1SMN1; SMN2TP53TSHRKDM4E
SCHEMBL9444420 0.81 ESR1 (0.64) NPC1TSHRPOLBHIF1AALDH1A1
SCHEMBL27891848 0.80 TP53 (0.42) NPC1SMN1; SMN2TP53TSHRKDM4E
SCHEMBL1445699 0.78 KDM4E (0.50) NPC1SMN1; SMN2TP53TSHRKDM4E
Hydrochloric Acid SCHEMBL7182544 0.77 ALDH1A1 (0.57) TSHRLMNAPOLBHIF1AALDH1A1
SCHEMBL2839207 0.76 HSD17B10 (0.59) NPC1SMN1; SMN2TP53TSHRKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105603436-A Composite corrosion inhibitor and preparation method thereof CHANGCHUN INST APPLIED CHEMISTRY CAS 2016-05-25 CN disclosed