Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.51 |
| ▸ | HTR2C | P28335 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | MAOA | P21397 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | GPR3 | P46089 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.36 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19786102 | 0.79 | HTR2A (0.49) | HTR2AHTR2CALOX15MAPK1HSD17B10 | |
| SCHEMBL23116646 | 0.76 | PRCP (0.48) | HTR2AHTR2CALOX15MAPK1HSD17B10 | |
| SCHEMBL26836970 | 0.73 | HTR2A (0.63) | HTR2AHTR2CALOX15MAPK1HSD17B10 | |
| SCHEMBL6644840 | 0.72 | HTR2A (0.44) | HTR2AHTR2CALOX15MAPK1HSD17B10 | |
| SCHEMBL9880075 | 0.71 | HTR2A (0.40) | HTR2AHTR2CALOX15MAPK1HSD17B10 | |
| SCHEMBL9880074 | 0.71 | HTR2A (0.40) | HTR2AHTR2CALOX15MAPK1HSD17B10 | |
| SCHEMBL10686008 | 0.71 | HTR2C (0.56) | HTR2AHTR2CALOX15MAPK1HSD17B10 | |
| SCHEMBL8793251 | 0.70 | HTR2A (0.44) | HTR2AHTR2CALOX15MAPK1HSD17B10 | |
| SCHEMBL26836968 | 0.70 | HTR2A (0.63) | HTR2AHTR2CALOX15MAPK1HSD17B10 | |
| SCHEMBL9880058 | 0.69 | HTR2C (0.39) | HTR2AHTR2CALOX15MAPK1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105579455-B | The methyl β carbolines of fluorine 9 | 音频治疗制药有限公司 | 2017-07-28 | — | — | CN | disclosed |
| CN-105579455-A | Fluor-9-methyl-[beta]-carbolines | AUDIOCURE PHARMA GMBH | 2016-05-11 | — | — | CN | disclosed |